Preparation, Characterization, and Antimicrobial Activity of Polyaniline and Fe2O3/Polyaniline Composite Nanoparticle
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Abstract
An oxidative polymerization approach was used to create polyaniline (PANI) and Fe2O3 /PANI nanoparticle combination. Various characterization approaches were used to investigate the structural, morphological, and Fe2O3 /PANI nanoparticle structures. The findings support the synthesis of polycrystalline nanoparticle PANI and Fe2O3 /PANI spherical nanoparticle composites. Gram-positive bacteria are tested for antibacterial activity. Various quantities of Nanoparticles of PANI and Fe2O3 /PANI nanoparticle composites were used to test Staph-aureus and gram-negative bacteria, E-coli, and candida species. PANI has antibacterial properties against all microorganisms tested. Fe2O3 /PANI nanoparticle composites, on the other hand, have higher antibacterial activity, as evidenced by the zone of inhibition. Bacterial inhibition zones are in S. aureus (positive), and E. coli are in good functioning order. With increasing concentrations of Fe2O3 /PANI nanoparticle composites, the inhibition zones of all bacteria are larger. Finally, the antimicrobial activity of Fe2O3 /PANI nanoparticle composite is characterized using a simplified mechanism based on electrostatic attraction. In this paper, a conductive polymer doped with iron nanoparticles was fabricated for the aim of testing it in the field of bacterial resistance.
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Yin C., Pan C., Liao X., Pan Y., and Yuan L., Regulating the interlayer spacing of vanadium oxide by in situ polyaniline intercalation enables an improved aqueous zinc-ion storage performance. ACS Applied Materials and Interfaces, 2021. 13(33): pp. 39347-39354.
Shaban M., Rabia M., Fathallah W., El-Mawgoud N.A., Mahmoud A., Hussien H., and Said O., Preparation and characterization of polyaniline and Ag/polyaniline composite nanoporous particles and their antimicrobial activities. Journal of Polymers and the Environment, 2018. 26(2): pp. 434-442.
Shuai C.-X., He Y., Su P., Huang Q., Pan D., Xu Q., Feng D., and Jiang Y., Integration of PEGylated polyaniline nanocoatings with multiple plastic substrates generates comparable antifouling performance. Langmuir, 2020. 36(31): pp. 9114-9123.
Qi X., Lu Z., You E.-M., He Y., Zhang Q.-e., Yi H.-J., Li D., Ding S.-Y., Jiang Y., and Xiong X., Nanocombing Effect Leads to Nanowire-Based, in-Plane, Uniaxial Thin Films. ACS Nano, 2018. 12(12): pp. 12701-12712.
Lee J., Kalin A.J., Yuan T., Al-Hashimi M., and Fang L., Fully conjugated ladder polymers. Chemical Science, 2017. 8(4): pp. 2503-2521.
Zhou T., Liang X., Wang P., Hu Y., Qi Y., Jin Y., Du Y., Fang C., and Tian J., A hepatocellular carcinoma targeting nanostrategy with hypoxia-ameliorating and photothermal abilities that, combined with immunotherapy, inhibits metastasis and recurrence. ACS Nano, 2020. 14(10): pp. 12679-12696.
Thangudu S., Kulkarni S.S., Vankayala R., Chiang C.-S., and Hwang K.C., Photosensitized reactive chlorine species-mediated therapeutic destruction of drug-resistant bacteria using plasmonic core–shell Ag and AgCl nanocubes as an external nanomedicine. Nanoscale, 2020. 12(24): pp. 12970-12984.
Liu Y., Yang Z., Huang X., Yu G., Wang S., Zhou Z., Shen Z., Fan W., Liu Y., and Davisson M., Glutathione-responsive self-assembled magnetic gold nanowreath for enhanced tumor imaging and imaging-guided photothermal therapy. ACS Nano, 2018. 12(8): pp. 8129-8137.
Barbero C., Salavagione H.J., Acevedo D.F., Grumelli D.E., Garay F., Planes G.A., Morales G.M., and Miras M.C., Novel synthetic methods to produce functionalized conducting polymers I. Polyanilines. Electrochimica Acta, 2004. 49(22-23): pp. 3671-3686.
Dong W., Li Y., Niu D., Ma Z., Gu J., Chen Y., Zhao W., Liu X., Liu C., and Shi J., Facile synthesis of monodisperse superparamagnetic Fe3O4 Core and hybrid and Au shell nanocomposite for bimodal imaging and photothermal therapy. Advanced materials, 2011. 23(45): pp. 5392-5397.
Li L., Liu Y., Hao P., Wang Z., Fu L., Ma Z., and Zhou J., PEDOT nanocomposites mediated dual-modal photodynamic and photothermal targeted sterilization in both NIR I and II window. Biomaterials, 2015. 41: pp. 132-140.
Kanicki J. and Skotheim T., Handbook of conducting polymers. Dekkker, New York, 1986. 543.
Jaque D., Maestro L.M., del Rosal B., Haro-Gonzalez P., Benayas A., Plaza J., Rodríguez E.M., and Solé J.G., Nanoparticles for photothermal therapies. Nanoscale, 2014. 6(16): pp. 9494-9530.
Amano K., Ishikawa H., Kobayashi A., Satoh M., and Hasegawa E., Thermal stability of chemically synthesized polyaniline. Synthetic Metals, 1994. 62(3): pp. 229-232.
Ibarra L., Yslas E., Molina M., Rivarola C., Romanini S., Barbero C., Rivarola V., and Bertuzzi M., Near-infrared mediated tumor destruction by photothermal effect of PANI-Np in vivo. Laser Physics, 2013. 23(6): pp. 066004-066007.
Gao D., Gao L., Zhang C., Liu H., Jia B., Zhu Z., Wang F., and Liu Z.J.B., A near-infrared phthalocyanine dye-labeled agent for integrin αvβ6-targeted theranostics of pancreatic cancer. 2015. 53: pp. 229-238.
Mattioli-Belmonte M., Giavaresi G., Biagini G., Virgili L., Giacomini M., Fini M., Giantomassi F., Natali D., Torricelli P., and Giardino R., Tailoring biomaterial compatibility: in vivo tissue response versus in vitro cell behavior. The International Journal of Artificial Organs, 2003. 26(12): pp. 1077-1085.
Laurencin C.T. and Elgendy H., The biocompatibility and toxicity of degradable polymeric materials: implications for drug delivery. Site specific drug delivery. New York: Wiley, 1994: pp. 27-46.
Collazos-Castro J.E., Polo J.L., Hernández-Labrado G.R., Padial-Cañete V., and García-Rama C., Bioelectrochemical control of neural cell development on conducting polymers. Biomaterials, 2010. 31(35): pp. 9244-9255.
Ravichandran R., Sundarrajan S., Venugopal J.R., Mukherjee S., and Ramakrishna S., Applications of conducting polymers and their issues in biomedical engineering. Journal of the Royal Society Interface, 2010. 7(suppl_5): pp. S559-S579.