Psoriasis Treatment by Using Narrowband-UVB Phototherapy
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Abstract
Ultraviolet light radiation is applied to treat Plaque Psoriasis disease by targeted phototherapy. This is available through Narrowband-UVB light radiation devices peaked at wavelength 311 nm. Ten cases were chosen as a study group, 8 males aged 22-40 years old, and 2 females aged 25 and 32 years old who were exposed to ultraviolet light radiation. Their recovery or improvement was followed weekly. Different doses were used according to the severity of the lesion and as a trial for the outcome. The dose was given two times a week, starting with 200mJ/cm2, and subsequently increased by 100 or 200 mJ/cm2 reaching a maximum dose as tolerated by each individual patient. Improvement was observed after 4 – 6 weeks. The patient stays in the treatment cabinet for a few seconds to several minutes according to the individual case which depends on the area of the body being treated. Treatment was stopped for two patients due to in toleration to the recommended dose. It was observed that good treatment results were obtained for the other 8 patients. The recovery rate from the disease was in the range of 50-100%. This is depending on the duration of the occurrence of the disease and the reduction of the size of the affected area on the skin for each individual patient after treatment.
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© 2023 The Author(s). Published by College of Science, University of Baghdad. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License.
References
Hearn R., Kerr A., Rahim K., Ferguson J., and Dawe R., Incidence of skin cancers in 3867 patients treated with narrow‐band ultraviolet B phototherapy. British Journal of Dermatology, 2008. 159(4): pp. 931-935.
Juzeniene A. and Moan J., Beneficial effects of UV radiation other than via vitamin D production. Dermato-endocrinology, 2012. 4(2): pp. 109-117.
Walker D. and Jacobe H., Phototherapy in the age of biologics. Seminars in Cutaneous Medicine and Surgery, 2011. 30(4): pp. 190-198.
Campbell J., Safe and effective use of phototherapy and photochemotherapy in the treatment of psoriasis. British Journal of Nursing, 2020. 29(10): pp. 547-552.
Nestle F.O., Kaplan D.H., and Barker J., Mechanisms of disease: psoriasis. New England Journal of Medicine, 2009. 361(5): pp. 496-509.
Turkiewicz A.M. and Moreland L.W., Psoriatic arthritis: current concepts on pathogenesis‐oriented therapeutic options. Arthritis Rheumatism, 2007. 56(4): pp. 1051-1066.
Kimball A.B., Jacobson C., Weiss S., Vreeland M.G., and Wu Y., The psychosocial burden of psoriasis. American journal of clinical dermatology, 2005. 6(6): pp. 383-392.
Mai S.-N., Pham G.-P., Van Toi V., Huynh K., and Pham T.-T.-H., Using UVB 311 nm Narrow-Band Medical Lamp for the Treatment of Psoriasis. International Conference on the Development of Biomedical Engineering in Vietnam, 2018: pp. 413-419.
Totonchy M.B. and Chiu M.W., UV-based therapy. Dermatologic clinics journal, 2014. 32(3): pp. 399-413.
Knuckles M.L., Levi E., and Soung J., Defining and treating moderate plaque psoriasis: a dermatologist survey. Journal of Dermatological Treatment, 2018. 29(7): pp. 658-663.
Cohen P.R., Hematologic-related malignancy-induced eosinophilic dermatosis (He Remained): an eosinophilic dermatosis predominantly associated with chronic lymphocytic leukemia. Journal of the American Academy of Dermatology, 2020. 82(1): pp. e13-e14.
Ralston S.H., Penman I.D., Strachan M.W., and Hobson R., Davidson's Principles and Practice of Medicine E-Book. 2018: Elsevier Health Sciences.
Mehrmal S., Uppal P., Giesey R.L., and Delost G.R., Identifying the prevalence and disability-adjusted life years of the most common dermatoses worldwide. Journal of the American Academy of Dermatology, 2020. 82(1): pp. 258-259.
Michalek I., Loring B., and John S., A systematic review of worldwide epidemiology of psoriasis. Journal of the European Academy of Dermatology Venereology, 2017. 31(2): pp. 205-212.